It's Ducati domination at the moment as Marquez is the only non-Ducati rider inside the top five.
Marini takes day-one honours in Valencia with Martin, Miller, Marquez and Bastianini rounding out the top five.
Wow! Marini goes nearly four tenths clear of Marquez who has gone second.
We have the first sub 1m 31s lap of the weekend as Miller blasts his way to the top of the leaderboard.
There's just ten minutes remaining so time attack runs won't be far away.
Big moment between Yamaha riders as Quartararo puts a move on Darryn Binder at the final corner. There was contact made.
Ducati are on the march as Marini goes quickest and Jorge Martin jumps into third.
Bagnaia makes a rare top ten appearance on day-one as he goes seventh fastest.
Cal Crutchlow is next to crash at turn two and is not happy.
Quartararo, Marini, Miller and Rins are separated by just +0.089s at the moment.
Thankfully the early crash-fest seems to have stopped as Luca Marini and Jack Miller have moved into the top three.
Marquez' turn one crash occured at just under 130 km/h. A very fast fall for the Honda man.
Make that four fallers early on as Aprilia's Aleix Espargaro has gone down at turn five.
What is going on at the start of FP2 as Marquez is next to crash, this time at turn one.
Fabio Di Giannantonio is down at turn two.
Morbidelli has gone down in sector one. The Yamaha rider appears to be ok.
Bagnaia has had an early off track moment after running wide at turn eight.
And we're underway with FP2 in Valencia!
Good afternoon and welcome back to Friday practice at the Valencia MotoGP. Coming up shortly is FP2.
Quartararo tops FP1 with Bagnaia only 16th. The same result on Sunday and the Yamaha rider would be crowned world champion.
It doesn't appear like many riders are opting to go for a time attack to end FP1. Most riders have instead not pitted and remained on used tyres with three minutes left.
Quartararo and the Yamaha appear to be making the difference as the lap develops, which was highlighted by Bastianini going fastest in sector one before losing chunks of time throughout the remainder of the lap.